Best Medicine

TV Series2026 –1h2 seasons · 22 episodes

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22Episodes, 2 seasons 0Member reviews 0Lists include it

Comedy Drama Medical

In Best Medicine a brilliant surgeon leaves Boston to become a small-town doctor where he spent childhood summers. Despite his medical skills, his rude manner alienates locals as he battles hidden phobias and struggles with personal connections.

Creator: Liz Tuccillo
Directors: Cathleen McFadyen Marcos Gonzalez Palma Michelle L. Keiser
Writers: Elizabeth Evans
Stars: Josh Charles Abigail Spencer Josh Segarra

Where it airs

FOXNetwork, from TVmaze

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Episode guide

Episode scores7.1 7.6 7.8 7.4 7.9 7.7 –––

Colours use member ratings when available, otherwise TVmaze/TMDB scores.

E1Be Careful What You Fish ForSep 20, 2026 · 1h 10m · While Martin continues to struggle with his blood phobia, a mermaid washes ashore in Port Wenn to the amazement of everyone in town; a well-meaning townsperson creates havoc while on prescribed oxygen.TVmaze 7.1

E2Breakin' in Is Hard to DoSep 29, 2026 · 1h · When the Port Wenn pharmacy is robbed, including Louisa's critical time-sensitive medicine, Martin deduces that the culprit desperately needs his help; Greg and George clash with a rival food truck owner; Sarah tries to bond with Eden; Martin is on the receiving end of a special brand of Port Wenn affection.TVmaze 7.6

E3Crate ExpectationsOct 6, 2026 · 1h · The citizens of Port Wenn get competitive during their annual floating crate race; Martin tries to give important medical advice when three men have positive pregnancy tests; former record-holder Sarah coaches Peter in the art of crate racing.TVmaze 7.8

E4No Place Like OmOct 13, 2026 · 1h · As Martin desperately tries to leave Port Wenn to meet Eden in Boston for the weekend, he must first investigate the extremely strange behavior of three patients who have all recently visited a meditation retreat; Mark is affected by the high school's graduation; Sarah's first guest in her rented spare room is none other than ex-paramour Eddie McCroy.TVmaze 7.4

E5Hare Today, Gone TomorrowOct 20, 2026 · 1h · When the wife of a traveling magician duo dies at the Salty Breeze, Martin must help the husband who is unable to grasp that she is gone; Martin gets a new male medical monitor who has an instant connection to Louisa.TVmaze 7.9

E6Can't Stop the HealingNov 3, 2026 · 1h · Martin works to debunk the sudden miraculous cures for the people of Port Wenn when self-proclaimed homeopath Savannah returns to town; Martin becomes acutely aware of Louisa and Parker's new connection.TVmaze 7.7

E7Love Is a BattlefieldNov 10, 2026 · 1h · Martin becomes concerned when during the Port Wenn Revolutionary War reenactment, some of the citizens start displaying tremors and odder-than-usual behavior; Martin is affected by Louisa's new relationship with Parker.Not rated yet

E8Back to the SutureAirs Nov 17, 2026 · 1h · When he discovers that his predecessor, the beloved Dr. Reese, had diagnosed a patient's brain tumor moments before he died, Martin, with Louisa's help, must deduce who it was in order to save them.Not rated yet

E9The Song Good-ByeAirs Nov 24, 2026 · 1hNot rated yet

Top cast

Full cast and crew

Josh CharlesDr. Martin Best Abigail SpencerLouisa Gavin Josh SegarraSheriff Mark Mylow Annie PottsSarah Best CreeElaine Denton Stephen SpinellaGreg Garrison Jason VeaseyGeorge Brady

Cast from TVmaze. People photos show only when a licensed image exists.

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Details

Premiered: January 4, 2026
Status: Running
Network: FOX
Country of origin: United States
Language: English
Episode runtime: 1h
Official site: fox.com/detail/series/SER262467MJOW/
TVmaze ID: 84556